U.S. Bio-Detection Homeland Security & Defense – Technology & Market – 2011-2016

Description

Publication: Q4 2010, Pages: 210, Tables & Figures: 118

2011-2016 Market: $12 Billion, 72% 3rd Generation Detectors, 19 Submarkets

$2.6 Billion by 2016

Despite nine years of intensive RDT&E and bio-terror mitigation programs implementation, at a cost of more than $50 billion, virtually all significant targets are as vulnerable to biological terror today as they were in September 2001.
In the words of President Obama: “we know that the successful deployment of a biological weapon – whether it is sprayed into our cities or spread through our food supply – could kill tens of thousands of Americans and deal a crushing blow to our economy.”
Meeting this challenge will require, among other things, shortening the bio-attack alarm response time, premium detection sensitivity and selectivity at a reasonable cost of ownership.
We forecast that over the next five years, led by 3rd generation technologies the US bio-detection market (including systems sale, service, consumables and upgrades) will grow from $1.3 billion in 2010 to $2.6 billion by 2016.
With more than 210 pages, 41 tables and 77 figures, granulated into more than 90 sub-markets this report represents a comprehensive bio-detection technologies and markets.
The report delves into:
  • Market by systems sales, upgrade and service markets
  • Market by first, second and third generation technologies
  • Market by indoor, outdoor, hand-held and mobile labs segment
  • Market by end user (e.g. 1st responders)
  • Systems prices
  • Installed base by product and user categories
  • Leading US bio-security projects
  • 27 vendors and their products
  • Current and pipeline technologies (e.g. advanced collectors-concentrators, reagent-less triggers, DNA-based diagnostics, antigen/anti-body methods, signal analysis algorithms)
  • Competitive analysis (e.g. barriers to entry, barriers to substitution, competitive rivalry)
  • Business opportunities (e.g. emerging threats, human and animal sentinel surveillance, reagent-less detection assays, IC3 compatibility)
  • SWOT analysis
  • Market drivers and inhibitors
  • And more…
Table of Contents Table of Contents
Download TOC as PDF
1 Executive Summary
1.1 Main Findings
1.2 Main Conclusions
1.3 Bio-Detection Market Forecast – 2011-2016
1.3.1 Overview
1.3.2 Systems and Service & Upgrade Markets – 2011-2016
1.3.3 Systems & Service Market by Modality – 2011-2016
1.3.4 Systems & Service Market by Technology Generation – 2011-2016
1.4 Bio-Detection – Next Generation Business Opportunities
1.5 Technologies Outlook
2 Introduction
2.1 Scope
2.2 Methodology
2.2.1 Research Methods
2.2.2 Report Structure
2.2.3 Assumptions
2.3 Who is This Report For?
3 Bio-Detection Market – Drivers
4 Bio-Detection Market – Inhibitors
5 Bio-Detection Industry Competitive Analysis
6 Bio-Detection Industry SWOT Analysis
7 Bio-detection Market Dynamics
8 Defending Against Bioterrorism
8.1 Definition of Bioterrorism
8.2 The Threat of Bioterrorism
8.3 How Real Is The Bioterrorism Threat?
8.4 Bio-Defense Programs
8.4.1 Strategy
8.4.2 Project BioWatch
8.4.3 Project BioSense
8.4.4 Project BioShield
8.5 Bio-Detection – The Industry
9 The Obama Administration Bio Terror Mitigation Strategy
9.1 Biosurveillance Network
9.2 Bio-Defense Funding
9.2.1 Overview
9.2.2 DHHS Bio-Defense Missions and Funding
9.2.3 DHS Bio-Defense Missions and Funding
9.2.4 DOD Bio-Defense Missions and Funding
9.2.5 DOA Bio-Defense Missions and Funding
9.2.6 EPA Bio-Defense Missions and Funding
9.3 The Obama Administration Bio-Defense Strategy
10 Bio-Detection – Technologies Overview
10.1 Bio-Detection Technology Challenges
10.1.1 Sampling the Environment
10.2 The Bio-Detection Process
10.2.1 Bio-Detectors in a Multitude of Ambient Settings
10.2.2 Bio-Detection Triggering
10.2.3 Collection of Particles
10.2.4 Bio-Particle Detectors
10.2.5 Bio-Agent Identification
11 Major Bio-Detection Technological Challenges
11.1 Challenge 1 – Detection of Small Particle Concentration
11.2 Challenge 2 – Eliminating Bio Background
11.3 Challenge 3 – Expensive Reagents
11.4 Challenge 4 – Expensive Equipment Maintenance
11.5 Challenge 5 – Adapting Equipment to Changing Environments
11.6 Challenge 6 – Dealing With Emerging Threats
12 Bio Detection Technologies Review & Outlook – 2011-2016
12.1 Bio-Detection – Core Technologies Comparison
12.2 Collector/Concentrator Core Technologies
12.3 Cyclone Collectors
12.4 Variable Particle-Size Impactor
12.5 Virtual Impactors
12.6 Impingers
12.7 Reagentless Trigger Core Technologies
12.7.1 Flow Cytometry
12.7.2 Particle Sizing
12.7.3 Gas Chromatography
12.7.4 Trigger Technologies – Drivers
12.7.5 Trigger Technologies – Inhibitors
12.8 DNA Based Diagnostic Core Technologies
12.8.1 Overview of DNA-Based Detection
12.8.2 Polymerase Chain Reaction (PCR)
12.8.3 DNA / RNA Microarrays
12.8.4 DNA Technology Drivers
12.8.5 DNA Technology Inhibitors
12.9 Antibody-Antigen Diagnostic Core Technologies
12.9.1 Overview of Antibody-Antigen Reaction
12.9.2 Hand-Held Immuno-Chromatographic Assays (HHA)
12.9.3 Magnetic Microbead-Base Assays
12.9.4 Microfluidic Devices – "Lab on a Chip"
12.9.5 Fluorescence Imaging
12.9.6 Electrochemical-Luminescence (ECL)
12.9.7 Antibody/Antigen Technology – Drivers
12.9.8 Antibody/Antigen Technology – Inhibitors
12.1 Signal Analysis Algorithms
12.10.1 Clustering / Classifier Algorithms
12.10.2 Image Analysis Algorithms
12.10.3 Decision Algorithms
12.10.4 Algorithm Drivers
12.10.5 Algorithm Inhibitors
12.11 Rapid Microbiological Technologies
13 Biological Detection – Overview by Application
13.1.1 Application 1 – Emergency Responder Hand-Held Detectors
13.1.2 Application 2 – Emergency Responder Mobile Labs
13.1.3 Application 3 – Indoor Standoff Detectors
13.1.4 Application 4 – Outdoor Standoff Detectors
14 U.S. Bio-Detection Systems Market Outlook – 2011-2016
14.1 Methodology
14.2 Bio-Detection Systems Sales – 2011-2016
14.2.1 Bio-Detection Systems Revenue Sales by Generation Forecast – 2011-2016
14.2.2 Bio-Detection Systems Sales by Modality – 2011-2016
14.3 Bio-Detection Systems Quantity Sales – 2011-2016
14.3.1 Bio-Detection Systems Quantity Sales by Generation – 2011-2016
14.3.2 Bio-Detection Systems Quantity Sales by Modality – 2011-2016
14.4 Outdoor Bio-Detection Systems Market – 2011-2016
14.4.1 Outdoor Standoff Detection Systems Revenue Sales Outlook – 2011-2016
14.4.2 Outdoor Standoff Detection Systems Quantity Sales Outlook – 2011-2016
14.5 Indoor Bio-Detection Systems Market– 2011-2016
14.5.1 Indoor Standoff Systems Detection Sales – 2011-2016
14.5.2 Indoor Standoff Systems Unit Sales – 2011-2016
14.6 First Responder Hand-Held Bio-Detection Systems Market – 2011-2016
14.6.1 First Responder Hand-Held Systems Sales – 2011-2016
14.6.2 First Responder Hand-Held Systems Quantity Sales – 2011-2016
14.7 Mobile Bio-Detection Labs Market – 2011-2016
14.7.1 First Responder Mobile Labs Sales – 2011-2016
14.7.2 First Responder Mobile Labs Quantity Sales – 2011-2016
15 Service & Upgrade Business – 2011-2016
15.1 Bio-Detection Service & Upgrade Business by Modality – 2011-2016
15.2 Bio-Detection Service Business by Technology Generation – 2011-2016
16 Business Opportunities in Bio-Detection – 2011-2016
16.1 Historical Perspective
16.1.1 A Market Waiting for Transition
16.1.2 The Current and Future HLS Bio-Defense Strategy for Detection
16.1.3 Factors Affecting Biological Detectors Deployment and Technologies – 2011-2016
16.1.4 Biological Detection Technology Timeline
16.2 Next Generation HLS Bio-Detection Systems Business Opportunities
16.2.1 Overview
16.2.2 Business Opportunity 1 – Emerging Threats
16.2.3 Business Opportunity 2 – Human Sentinel Surveillance System
16.2.4 Business Opportunity 3 – Animal Sentinel Surveillance System
16.2.5 Business Opportunity 4 – Biological IC3 – Biological Threat Assessment Intelligence Command, Control, and Communication Infrastructure
16.2.6 Business Opportunity 5 – Reducing False Alarms – Lesser False Positives and False Negatives
16.2.7 Business Opportunity 6 – Reducing Cost – Minimizing Use of Non-Reusable Reagents
16.3 Outdoor Standoff Biological Detectors
16.3.1 Business Opportunity 7 – Bioagent Autonomous Networked Detectors (BAND)
16.3.2 Business Opportunity 8 – Rapid Automated Biological Identification System (RABIS)
16.3.3 Business Opportunity 9 – First Responder Portable Hand-Held Detector
16.3.4 Business Opportunity 10 – First Responder Mobile Biological Detection Station
16.3.5 Business Opportunity 11 – Regional Automatic Detector – Outdoor Standoff Detectors
16.3.6 Business Opportunity 12 – Networked Automatic Detector – Indoor Standoff Detectors
16.3.7 Business Opportunity 13 – External Spread of Bioagent Detection
16.3.8 Business Opportunity 14 – Internal Spread of Bioagent
16.4 Other Bio-Detection Technologies – Business Opportunities
16.4.1 Business Opportunity 15 – "Lab on a Chip" – Miniature Detection Devices
16.4.2 Business Opportunity 16 – Reagentless Specific Detection Assays
16.4.3 Business Opportunity 17 – Laser Induced Breakdown Spectroscopy (LIBS)
16.4.4 Business Opportunity 18 – Raman Spectroscopy-based Reagentless Detection
16.5 Future Technologies and Systems
17 Bio-Detection – Personnel Considerations
17.1 Background – Personnel
17.2 Personnel Training
18 Vendors
18.1 20/20 GeneSystems Inc.
18.2 Advnt Biotechnologies
18.3 Agilent Technologies
18.4 Alexeter Technologies
18.5 ANP Technologies, Inc.
18.6 BAS - Biological Alarm Systems Ltd. (Israel)
18.7 BD Biosciences Immunocytometry Systems
18.8 Bertin Technologies
18.9 BioDefense Corporation
18.1 BioDETECT AS
18.11 BioSentinel Pharmaceuticals LLC
18.12 3M Microbiology (Biotrace International, Ltd.)
18.13 BioTraces, Inc.
18.14 BioVeris Corporation
18.15 Biral
18.16 Cepheid
18.17 Commonwealth Biotechnologies, Inc.
18.18 Dycor Technologies Ltd.
18.19 Environics Oy
18.2 Evogen, Inc.
18.21 General Dynamics Canada
18.22 GenPrime, Inc.
18.23 Groton Biosystems
18.24 Haztech Systems, Inc.
18.25 Idaho Technology, Inc.
18.26 JMAR Technologies, Inc.
18.27 New Horizons Diagnostics
18.28 Proengin
18.29 QTL Biodetection
18.3 Research International
18.31 Response Biomedical
18.32 Roche Applied Science
18.33 Smiths Detection
18.34 Tetracore, Inc.
19 Prices of Bio-Detection Equipment
20 Appendix A: The Threat of Bioweapons
20.1 Use of Bioweapons – Historical Perspective
20.2 Biological Terror – Bacterial Agents
20.2.1 Anthrax
20.2.2 Cholera
20.2.3 Plague
20.2.4 Tularemia
20.3 Biological Terror – Viral Agents
20.3.1 Smallpox
20.3.2 Hemorrhagic Fever Viruses
20.3.3 Venezuelan Equine Encephalitis
20.4 Biological Terror – Rickettsiae Agents
20.4.1 Q Fever
20.4.2 Typhus
20.5 Biological Terror – Toxins
20.5.1 Botulinum Toxin
20.5.2 Ricin
20.5.3 Saxitoxin
20.5.4  Staphylococcal Enterotoxin B (SEB)
21 Appendix B: Legal Issues
21.1 International / European Legislation / Agreements
21.1.1 The Biological and Toxin Weapons Convention (BTWC) 1972
21.2 U.S. Bioterrorism Legislation
Figures/Tables Tables
Table 1 US HLS & Defense Bio-Detection Systems and Service Market [$M] 2010 & 2016 – by Product Classification
Table 2 U.S. HLS Bio-Detection Systems and Service Market Forecast [$ Million] – 2010-2016
Table 3 U.S. HLS Bio-Detection Systems & Service (S&S) Market Forecast by Expenditure Share [%] – 2010-2016
Table 4 U.S. HLS Bio-Detection Systems & Service Market by Portability [$ Million] – 2010-2016
Table 5 U.S. HLS Bio-Detection Systems & Service Market by Modality Share [%] – 2010-2016
Table 6 Bio-Detection Systems Sales by Generation [$ Million] – 2010-2016
Table 7 Bio-Detection Systems Sales by Generation [%] – 2010-2016
Table 8 Bio-Detection Service and Upgrade Business Forecast by Technology Generation [$ Million] – 2010-2016
Table 9 Bio-Detection Service and Upgrade Business Forecast by Technology Generation Share [%] – 2008-2014
Table 10 Evolution of Bio-detection Market Dynamics - 2010-2014
Table 11 U.S. Federal HLS-HLD Bio-Defense Funding [$ Million], by Agency – FY2001-FY2011
Table 12 Comparison of Attributes of Bio-Detection Technologies
Table 13 Bio-Detection Systems Sales by Generation [$ Million] – 2010-2016
Table 14 Bio-Detection Systems Sales by Generation Share [%] – 2010-2016
Table 15 Bio-Detection Consolidated Sales by Modality [$M] – 2010-2016
Table 16 Bio-Detection Systems Sales by Modality Share [%] – 2010-2016
Table 17 Bio-Detection Systems Quantity Sales by Generation [Units] – 2010-2016
Table 18 Bio-Detection Systems Quantity Sales by Generation Share [%] – 2010-2016
Table 19 Bio-Detection Systems Quantity Sales by Modality [Units] – 2010-2016
Table 20 Bio-Detection Systems Quantity Sales by Modality Share [%] – 2010-2016
Table 21 Outdoor Standoff Detectors Systems Sales by Generation [$ Million] – 2010-2016
Table 22 Outdoor Standoff Detectors Systems Sales by Generation Share [%] – 2010-2016
Table 23 Outdoor Standoff Detectors Systems Sales [Units] – 2010-2016
Table 24 Outdoor Standoff Detectors Systems Sales Share [%] – 2010-2016
Table 25 Indoor Standoff Systems Sales by Generation [$M] – 2010-2016
Table 26 Indoor Standoff Detectors Systems Sales by Generation Share [%] – 2010-2016
Table 27 Indoor Standoff Systems Sales by Generation [Units] – 2010-2016
Table 28 Indoor Standoff Detectors Systems Sales by Generation Share [%] – 2010-2016
Table 29 First Responder Hand-Held Detection Systems Sales [$M] by Generation – 2010-2016
Table 30 First Responder Hand-Held Detection Systems Sales by Generation Share [%] – 2010-2016
Table 31 First Responder Hand-Held Systems Sales [Units] by Generation – 2010-2016
Table 32 First Responder Hand-Held Systems Sales by Generation Share [%] – 2010-2016
Table 33 First Responder Mobile Labs Sales by Generation [$M] – 2010-2016
Table 34 First Responder Mobile Labs Sales by Generation Share [%] – 2010-2016
Table 35 First Responder Mobile Labs Sales by Generation [Units] – 2010-2016
Table 36 First Responder Mobile Labs Unit Sales by Generation Share [%] – 2010-2016
Table 37 Bio-Detection Service & Upgrade Business by Modality [$M] – 2010-2016
Table 38 Bio-Detection Service & Upgrade Business by Modality Share [%] – 2010-2016
Table 39 Bio-Detection – Service Business by Technology Generation [$M] – 2010-2016
Table 40 Bio-Detection Service Business Forecast by Technology Generation Share [%] – 2010-2016
Table 41  Prices of Bio-Detection Equipment

Figures
Figure 1 Cumulative Civilian Biodefense Funding by Agency, FY2001-FY2011 [$M]
Figure 2 US HLS & Defense Bio-Detection Systems and Service Market [$M] 2010 & 2016 – by Product Classification
Figure 3 U.S. HLS Bio-Detection Systems & Service Market [$ Million] – 2010-2016
Figure 4 U.S. HLS Bio-Detection Systems & Service Market Share [%] – 2010, 2013 & 2016
Figure 5 U.S. HLS Bio-Detection Systems & Service Market Forecast by Modality [$ Million] – 2010-2016
Figure 6 U.S. HLS Bio-Detection Systems & Service Market Forecast by Modality Share [%] – 2010, 2013 & 2016
Figure 7 Bio-Detection Systems Sales by Generation [$ Million] – 2010-2016
Figure 8 Bio-Detection Service Business by Technology Generation [$ Million] – 2010-2016
Figure 9 Types of Biological Detectors
Figure 10 Bio-Detection Industry Competitive Analysis
Figure 11 Bio-Detection Industry SWOT Analysis
Figure 12 Bio-Detection Strategy – Three Pillars Diagram
Figure 13 BioShield Timeline and Funding
Figure 14 Bio-Detection Responsibilities across the US Federal Bio-surveillance Network
Figure 15 U.S. Government HLS-HLD Bio-Defense Funding [$ Million] – FY2001-FY2011
Figure 16 Cumulative 2001-2011 Bio-Defense Funding [$Million], by Agency
Figure 17 Bio-Defense Funding Share [%], by Agency – 2001, 2006 & 2011
Figure 18 Comparison in Weight of Pathogens Between BW Agents and CW Agents [mg]
Figure 19 Typical Point Detection Automated Architecture (With a Combined Trigger/Cue)
Figure 20 Airborne Bacterial Concentration Fluctuation in a Single Day
Figure 21 Cross-Section of Cascade Impactor: PIXE International Corporation
Figure 22 TSI's Model 3317 System with Concentrator, GPS Receiver & Wireless Data Radio
Figure 23 Biological Detection Technologies – 2010-2016
Figure 24 Flow Cytometry
Figure 25 Gas Chromatography
Figure 26 Polymerase Chain Reaction
Figure 27 RT–PCR
Figure 28 Principles of Real-Time PCR
Figure 29 DNA Microarrays – Principles of Operation
Figure 30 Schematic for Antibody Protein
Figure 31 Hand Held Detectors: Alexeter Guardian Reader System and Tetracore Test Strips
Figure 32 Roche Applied Science – Light CyclerTM Model 1.2
Figure 33 Bio-Detection Systems Sales by Generation [$M] – 2010-2016
Figure 34 Bio-Detection Systems Sales by Generation Share [%] – 2010, 2013 & 2016
Figure 35 Bio-Detection Systems Sales by Modality [$M] – 2010-2016
Figure 36 Bio-Detection Systems Sales by Modality Share [%] – 2010, 2013 & 2016
Figure 37 Bio-Detection Systems Quantity Sales by Generation [Units] – 2010-2016
Figure 38 Bio-Detection Systems Quantity Sales by Generation Share [%] – 2010, 2013 & 2016
Figure 39 Bio-Detection Systems Quantity Sales by Modality [Units] – 2010-2016
Figure 40 Bio-Detection Systems Quantity Sales by Modality Share [%] – 2010, 2013 & 2016
Figure 41 Outdoor Systems Standoff Detectors Sales by Generation [$M] – 2010-2016
Figure 42 Outdoor Standoff Detectors Systems Sales by Generation Share [%] – 2010, 2013 & 2016
Figure 43 Outdoor Standoff Detectors Systems Sales [Thousand of Units] – 2010-2016
Figure 44 Outdoor Standoff Detectors Systems – Sales Share [%] – 2010, 2013 & 2016
Figure 45 Indoor Standoff Detectors Systems Sales by Generation [$M] – 2010-2016
Figure 46 Indoor Standoff Detectors Systems Sales by Generation Share [%] – 2010, 2013 & 2016
Figure 47 Indoor Standoff Systems Sales by Generation [Units] – 2010-2016
Figure 48 Indoor Standoff Systems Sales by Generation Share [%] – 2010, 2013 & 2016
Figure 49 First Responder Hand-Held Detection Systems Sales [$M] by Generation – 2010-2016
Figure 50 First Responder Hand-Held Detection Systems Sales by Generation Share [%] – 2010, 2013 & 2016
Figure 51 First Responder Hand-Held Detection Systems Sales by Generation [Units] – 2010-2016
Figure 52 First Responder Hand-Held Detection Systems Sales by Generation Share [%] – 2010, 2013 & 2016
Figure 53 First Responder Mobile Labs Sales by Generation [$M] – 2010-2016
Figure 54 First Responder Mobile Labs Sales by Generation Share [%] – 2010, 2013 & 2016
Figure 55 First Responder Mobile Labs Sales by Generation [Units] – 2010-2016
Figure 56 First Responder Mobile Labs Unit Sales by Generation Share [%] – 2010, 2013 & 2016
Figure 57 Bio-Detection Service & Upgrade Business Forecast by Modality [$M] – 2010-2016
Figure 58 Bio-Detection Service & Upgrade Business Forecast by Modality Share [%] – 2010, 2013 & 2016
Figure 59 Bio-Detection Service & Upgrade Business by Technology Generation [$M] – 2010-2016
Figure 60 Bio-Detection Service & Upgrade Business by Technology Generation [%] – 2010, 2013 & 2016
Figure 61 Factors Affecting Biological Detection Deployment and Technologies – 2010-2016
Figure 62 Bio-Detection Timeline
Figure 63 Civilians in China During the SARS Epidemic
Figure 64 A Typical Microfluidic Device
Figure 65 BAS101 Scheme
Figure 66 The Spraying of Anthrax from Aum Shinrikyo's Headquarters June 1993
Figure 67 Anthrax Spores and Disease
Figure 68 Cholera Bacteria
Figure 69 Pneumonic Plague – The Disease
Figure 70 Tularemia – The Disease
Figure 71 Smallpox Virus And Disease
Figure 72 Ebola Virus – Electron Microscopy Image
Figure 73 VEE – Venezuelan Equine Encephalitis Virus in the Olfactory Mucosa of a Mouse
Figure 74 Q Fever
Figure 75 Typhus Microbe – Electron Microscopy Image
Figure 76 Castor Plant And Structure For The Ricin Toxin
Figure 77  The Dinoflagellate Alexandrium Tamarense And Structure of Saxitoxin
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